There’s something truly comforting about a warm meal waiting for you at the end of a long day. Sheet pan dinners have a special place in my heart for their simplicity and ease, making them ideal for busy weeknights or relaxed weekends. One such meal that has quickly become a favorite in our home is Sheet Pan Honey Mustard Salmon and Brussels Sprouts. This dish brings a delightful harmony of flavors to the table and is sure to please any palate.
At the heart of this recipe are four succulent salmon fillets and a pound of halved Brussels sprouts, which together create a wholesome and nutritious meal. The dish is elevated with a tempting honey mustard glaze made from three tablespoons of honey and three tablespoons of Dijon mustard, combined with olive oil, garlic powder, paprika, and a sprinkle of salt and pepper. The sweetness of the honey beautifully balances the tanginess of the mustard, resulting in a rich flavor profile that keeps you coming back for more.
You’ll be thrilled to know that preparing this dish is as effortless as it is rewarding. Start by preheating your oven to 400°F (200°C). While the oven warms up, whisk together your honey, Dijon mustard, olive oil, garlic powder, paprika, salt, and pepper—all in one bowl. It’s then a simple matter of placing the salmon and Brussels sprouts on a sheet pan, drizzling the glaze over, tossing the vegetables, and letting the oven do the work. In just 15-20 minutes, you’ll have a meal that’s not only nourishing but incredibly flavorful.
This recipe is perfect for many occasions. Whether you’re looking for a cozy dinner on a chilly night or need an easy yet impressive dish for a potluck, this honey mustard salmon and Brussels sprouts is just the ticket. It’s straightforward yet elegant enough to impress your family and friends.

Why You’ll Love This Sheet Pan Honey Mustard Salmon and Brussels Sprouts
- Quick and Easy: This dish can be ready in about 30 minutes, making it a perfect option for busy schedules.
- Nutrient-Packed: Salmon is rich in omega-3 fatty acids, and Brussels sprouts are a great source of vitamins, ensuring a healthy meal.
- Minimal Cleanup: Cooking everything on one sheet pan means less time spent cleaning up after dinner.
- Customizable: The honey mustard glaze can be adjusted according to your taste, making this recipe very adaptable.
- Deliciously Comforting: The combination of flavors makes this dish feel like a warm hug on a plate.
Salmon Tips
When choosing your salmon for this recipe, look for fillets that have a vibrant pink color and moist texture. Fresh salmon should have a mild aroma, not a fishy smell. You can opt for wild-caught or farm-raised, depending on your preference. Also, check for any signs of browning or dryness at the edges, as this could indicate age. If frozen salmon is your choice, ensure that it has been properly thawed before cooking to ensure even cooking during baking.
Options for Substitutions
- Honey: Substitute with maple syrup for a different sweet twist.
- Dijon Mustard: You can use whole grain mustard for added texture.
- Brussels Sprouts: Try using green beans or asparagus for a change in vegetables.
- Olive Oil: Avocado oil is a great alternative for a higher smoke point.
- Paprika: Smoked paprika can add a delightful smoky flavor.
- Garlic Powder: Fresh minced garlic can provide a more robust garlic flavor.
Watch Out for These Mistakes
One common mistake is overcooking the salmon. Keep a close eye on your fillets as they bake; they should be flakily tender and never dry. Also, make sure that the Brussels sprouts are coated evenly with the glaze. If they aren’t, they may come out bland since they won’t have absorbed the flavor well.
Another point to consider is the thickness of your salmon fillets. Thicker pieces may require an extra few minutes in the oven, so adjust accordingly. Lastly, ensure that you preheat your oven fully before placing the sheet pan inside. This helps in achieving the best texture and doneness for both the salmon and Brussels sprouts.

What to Serve With Sheet Pan Honey Mustard Salmon and Brussels Sprouts?
Pair your honey mustard salmon and Brussels sprouts with a light side salad for a refreshing touch. A simple cucumber and tomato salad with a drizzle of balsamic vinaigrette can complement the meal beautifully. Additionally, a side of quinoa or brown rice would make for a wholesome addition, helping to soak up the delicious honey mustard sauce.
Storage Instructions
Store: Leftovers can be kept in an airtight container in the refrigerator for up to 3 days.
Freeze: You can freeze the cooked salmon and Brussels sprouts for up to 3 months. Just be sure to let them cool completely before placing them in freezer-safe bags.
Reheat: Reheating can be done on the stovetop over low heat or in the microwave for about 1-2 minutes or until warmed through.
Recipe Info
- Preparation Time: 10 minutes
- Cooking Time: 15-20 minutes
- Total Time: 25-30 minutes
- Level of Difficulty: Easy
- Servings: 4
Estimated Nutrition
Estimated nutrition for the whole recipe (without optional ingredients): Calories: 600-650, Protein: 45-50g, Fat: 25-30g, Carbohydrates: 45-50g.
Ingredients
- 4 salmon fillets
- 1 lb Brussels sprouts, halved
- 3 tablespoons honey
- 3 tablespoons Dijon mustard
- 2 tablespoons olive oil
- Salt and pepper to taste
- 1 teaspoon garlic powder
- 1 teaspoon paprika

Step-by-Step Instructions
Step 1: Preheat Oven and Prep Pan
Begin by preheating your oven to 400°F (200°C). This ensures that the salmon and Brussels sprouts cook evenly. While the oven is heating, prepare your sheet pan by lining it with parchment paper if you prefer easy cleanup.
Step 2: Make the Honey Mustard Mixture
In a medium bowl, whisk together the honey, Dijon mustard, olive oil, garlic powder, paprika, salt, and pepper. The mixture should be smooth and well combined, creating a flavorful glaze for your salmon and Brussels sprouts.
Step 3: Arrange Salmon and Brussels on a Sheet Pan
Place the salmon fillets on one side of the prepared sheet pan. On the other side, arrange the halved Brussels sprouts. Ensure there is space for them to roast properly without overcrowding.
Step 4: Coat and Toss
Drizzle the honey mustard mixture generously over the salmon fillets. Then, take the Brussels sprouts and pour the remaining glaze over them. Gently toss the Brussels sprouts to coat them evenly with the honey mustard mixture.
Step 5: Bake
Carefully place the sheet pan in the preheated oven. Bake for 15-20 minutes, checking for doneness at around the 15-minute mark. The salmon should be opaque and flake easily with a fork, while the Brussels sprouts should be tender.
Step 6: Serve Hot
Once cooked, remove the pan from the oven and allow it to sit for a minute. Serve the salmon and Brussels sprouts hot, garnishing with additional mustard or a sprinkle of fresh herbs if desired.
In conclusion, this Sheet Pan Honey Mustard Salmon and Brussels Sprouts is not just a meal but an experience. It simplifies dinner time without sacrificing flavor or nutrition. I encourage you to try this recipe, explore variations, and share your experiences. Your feedback is invaluable, and who knows—you may just find a new family favorite!
Print
Sheet Pan Honey Mustard Salmon and Brussels Sprouts
- Prep Time: 10 minutes
- Cook Time: 20 minutes
- Total Time: 30 minutes
- Yield: 4 servings 1x
- Category: Main Course
- Method: Baking
- Cuisine: American
- Diet: Pescatarian
Description
A comforting and nutritious sheet pan dinner featuring salmon fillets and Brussels sprouts drizzled with a delicious honey mustard glaze.
Ingredients
- 4 salmon fillets
- 1 lb Brussels sprouts, halved
- 3 tablespoons honey
- 3 tablespoons Dijon mustard
- 2 tablespoons olive oil
- Salt and pepper to taste
- 1 teaspoon garlic powder
- 1 teaspoon paprika
Instructions
- Preheat your oven to 400°F (200°C).
- Whisk together the honey, Dijon mustard, olive oil, garlic powder, paprika, salt, and pepper in a medium bowl.
- Place the salmon fillets on one side of the prepared sheet pan and arrange the halved Brussels sprouts on the other side.
- Drizzle the honey mustard mixture over the salmon fillets and pour the remaining glaze over the Brussels sprouts. Toss the Brussels to coat.
- Bake for 15-20 minutes, checking for doneness at the 15-minute mark.
- Serve the salmon and Brussels sprouts hot, optionally garnishing with additional mustard or fresh herbs.
Notes
Pair with a light side salad or quinoa for a wholesome meal. Leftovers can be stored in the refrigerator for up to 3 days.
Nutrition
- Serving Size: 1 serving
- Calories: 620
- Sugar: 20g
- Sodium: 400mg
- Fat: 28g
- Saturated Fat: 4g
- Unsaturated Fat: 18g
- Trans Fat: 0g
- Carbohydrates: 45g
- Fiber: 6g
- Protein: 50g
- Cholesterol: 80mg